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(Acyl)polyamines
Small compounds
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Amino acids
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Biogenic amines
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Nucleosides & nucleotides
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Quaternary amines
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Organic acids
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Others
-- 1-Guanidino-6-hydroxy-3,5-dihydro-ß-carboline
-- 5-Methoxytryptamine
-- Bis(agmatine)oxalamide
-- DOPAC
-- Epinine
-- FrPbAII
-- Glucose
-- Glycerin
-- Nigriventrine
-- Phenylacetamide
-- PwTx-I
-- PwTx-II
-- Taurine
-- Urea
Analytical tools
Contact us PwTx-I
General Description Name Value Level S-2 / C-2 Discovered 2005 / P. bistriata Synonym 6-Hydroxytrypargine / 6-HT Molecular formula C₁₅H₂₁N₅O CAS 1188405-18-6 SMILES OC(C=C1)=CC2=C1NC3=C2CCNC3CCCNC(N)=N
InChI InChI=1S/C15H21N5O/c16-15(17)19-6-1-2-13-14-10(5-7-18-13)11-8-9(21)3-4-12(11)20-14/h3-4,8,13,18,20-21H,1-2,5-7H2,(H4,16,17,19)
Precursor 1 [M+H]⁺ 288.18189 Precursor 2 Precursor 3 HDX 7 Precursor HDX 1 [M(D₇)+D]⁺ 296.23210 Precursor HDX 2 Precursor HDX 3 Rt Rt HDX
MS/MS fragments m/z Molecular formula Annotation
Recorded MS/MS spectra pdf Precursor Co-eluting Spider Source Author
References Title Reference Spider Name Content Link Structure determination of hydroxytrypargine: A new tetrahydro-beta-carboline toxin from the venom of the spider Parawixia bistriata L. M. M. Cesar, C. F. Tormena, M. R. Marques, G. V. J. Silva, M. A. Mendes, R. Rittner, M. S. Palma, Helv. Chim. Acta 2005, 88, 4, 796-801 P. bistriata PwTx-I ESI-MS/MS Link Monoamine oxidase inhibitory activities of indolylalkaloid toxins from the venom of the colonial spider Parawixia bistriata: functional characterization of PwTx-I D. M. Saidenberg, M. A. B. Ferreira, T. N. Takahashi, P. C. Gomes, L. M. M. Cesar-Togonoli, L. C. da Silva-Filho, C. F. Tormena, G. V. J. da Silva, M. S. Palma, Toxicon 2009, 54, 6, 717-724 P. bistriata PwTx-I (3) Synthesis Link Effects of spider venom toxin PwTx-I (6-hydroxytrypargine) on the central nervous system of rats L. M. M. Cesar-Tognoli, S. D. Salamoni, A. A. Tavares, C. F. Elias, J. C. da Costa, J. C. Bittencourt, M. S. Palma, Toxins 2011, 3, 2, 142-162 PxTx-I / 6-HT Link
Spider species Spider species Family Discovered Parawixia bistriata Araneidae 2005 / L. M. M. Cesar