Inosine

General Description

NameValue
LevelS-1 / C-1
Discovered1975 / L. reclusa
Synonym
Molecular formulaC₁₀H₁₂N₄O₅
CAS58-63-9
SMILESOC1[C@@H](CO)O[C@@H](N2C=NC3=C2N=CNC3=O)C1O
InChIInChI=1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6+,7?,10-/m1/s1
Precursor 1 [M+H]⁺269.08805
Precursor 2
Precursor 3
HDX4
Precursor HDX 1 [M(D₄)+D]⁺274.11943
Precursor HDX 2
Precursor HDX 3
Rt2.83
Rt HDX2.31

MS/MS fragments

m/zMolecular formulaAnnotation
137.04579C₅H₅N₄O[hypoxanthine+H]⁺

Recorded MS/MS spectra

pdfPrecursorCo-elutingSpiderSourceAuthor
Data269.08805InosineSigma AldrichY. M. Forster
Data269.08805A. robustusAlpha Biotoxin, BELY. M. Forster
DataHDXA. robustusAlpha Biotoxin, BELY. M. Forster
Data269.08805D. canitiesSpider Pharm, USAY. M. Forster
Data269.08805Eresus sp.2Fauna Laboratories Ltd., KAZY. M. Forster
Data269.08805P. bistriataProf. Dr. Wagner Ferreira dos Santos, BRAY. M. Forster
DataHDXP. bistriataProf. Dr. Wagner Ferreira dos Santos, BRAY. M. Forster
Data269.08805P. mexicanusSpider Pharm, USAY. M. Forster
Data269.08805P. tristisSpider Pharm, USAY. M. Forster
DataHDXP. tristisSpider Pharm, USAY. M. Forster
Data269.08805S. grossaSpider Pharm, USAY. M. Forster

References

TitleReferenceSpiderNameContentLink
Partial characterization of the low molecular weight fractions of the extract of the venom apparatus of the brown recluse spider and its hemolymphC. R. Geren, T. K. Chan, D. E. Howell, G. V. Odell, Toxicon 1975, 13, 4, 233-238L. reclusaLink
Separation and identification of inosine in the Selenocosmia huwena spiderY. She, B. Xu, S. Liang, S. Li, Chinese Journal of Analytical Chemistry 1995, 23, 9, 1081-1083C. hainanusLink
The main products of the low molecular mass fraction in the venom of the spider Latrodectus menavodiA. Horni, D. Weickmann, M. Hesse, Toxicon 2001, 39, 425-428L. menavodiLink
The biological activity in mammals and insects of the nucleosidic fraction from the spider Parawixia bistriataM. C. A. Rodrigues, R. Guizzo, L. Gobbo-Neto, R. J. Ward, N. P. Lopes, W. F. dos Santos, Toxicon 2004, 43, 4, 375-383P. bistriataLink
Elucidation of the structure and synthesis of neuroprotective low molecular mass components of the Parawixia bistriata spider venomY. M. Forster, J. L. Green, A. Khatiwada, J. L. Liberato, P. A. Narayana Reddy, J. M. Salvino, S. Bienz, L. Bigler, W. Ferreira dos Santos, A. C. K. Fontana, ACS Chem Neurosci., 2020P. bistriataESI-MS/MSLink

Spider species

Spider speciesFamilyDiscovered
Atrax robustusAtracidae2020 / Y. M. Forster
Cyriopagopus hainanusTheraphosidae1995 / Y. She
Diguetia canitiesDiguetidae2020 / Y. M. Forster
Eresus sp.Eresidae2020 / Y. M. Forster
Latrodectus menavodiTheridiidae2001 / A. Horni
Loxosceles reclusaSicariidae1975 / C. R. Geren
Parawixia bistriataAraneidae2004 / M. C. A. Rodrigues
Physocyclus mexicanusPholcidae2020 / Y. M. Forster
Plectreurys tristisPlectreuridae2020 / Y. M. Forster
Steatoda grossaTheridiidae2020 / Y. M. Forster

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