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Serotonin

General Description

NameValue
LevelS-1 / C-1
Discovered1963 / div.
Synonym5-Hydroxytryptamine / 5-HT
Molecular formulaC₁₀H₁₂N₂O
CAS50-67-9
SMILESNCCC1=CNC2=C1C=C(O)C=C2
InChIInChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
Precursor 1 [M+H]⁺177.10224
Precursor 2 [M+H-NH₃]⁺160.07569
Precursor 3
HDX4
Precursor HDX 1 [M(D₄)+D]⁺182.13362
Precursor HDX 2
Precursor HDX 3
Rt4.31
Rt HDX3.48

MS/MS fragments

m/zMolecular formulaAnnotation
160.07569C₁₀H₁₀NO[M+H-NH₃]⁺
132.08078C₉H₁₀N
115.05423C₉H₇

Recorded MS/MS spectra

pdfPrecursorCo-elutingSpiderSourceAuthor
Data177.10224Serotonin HCl (CAS 153-98-0)FlukaY. M. Forster
Data177.10224A. robustusAlpha Biotoxin, BELY. M. Forster
DataHDXA. robustusAlpha Biotoxin, BELY. M. Forster
Data177.10224Desertosa sp.3Fauna Laboratories Ltd., KAZY. M. Forster
Data177.10224H. davidbowieAlpha Biotoxin, BELY. M. Forster
Data177.10224H. carolinensisSpider Pharm, USAY. M. Forster
DataHDXH. carolinensisSpider Pharm, USAY. M. Forster
Data177.10224L. praegrandisFauna Laboratories Ltd., KAZY. M. Forster
Data177.10224Lycosa sp.1Fauna Laboratories Ltd., KAZY. M. Forster
Data177.10224Lycosa sp.5Fauna Laboratories Ltd., KAZY. M. Forster
Data177.10224P. luctuosaFauna Laboratories Ltd., KAZY. M. Forster
DataHDXP. luctuosaFauna Laboratories Ltd., KAZY. M. Forster

References

TitleReferenceSpiderNameContentLink
5-Hydroxytryptamine content of some arthropod venoms and venom-containing partsJ. H. Welsh, C. S. Batty, Toxicon 1963, 1, 165-173div.5-Hydroxytryptaminepaper-chromatographyLink
5-Hydroxytryptamine content of Latrodectus mactans tredecimguttatus venom from gland extractsM. C. Pansa, G. M. Natalizi, S. Bettini, Toxicon 1972, 10, 85-86L. tredecimguttatus5-HydroxytryptamineLink
Phoneutria nigriventer venom. Pharmacology and biochemistry of its componentsIn: Venomous animals and their venoms (New York: Academic Press, 1973), S. Schenberg, F. A. Pereira-LimaP. nigriventer
Determination of biogenic amines in spider venom glands of nine typical Japanese species and chromatographic elution pattern analysis of venomous componentsK. Hagiwara, A. Tokita, A. Miwa, N. Kawai, Y. Murata, A. Uchida, T. Nakajima, Jpn. J. Sanit. Zool. 1991, 42, 2, 77-84C. japonicumLink
Identification of noradrenaline in venom from the funnel-web spider Hololena curtaR. Frew, M. G. Hamilton, P. M. Lundy, Toxicon 1994, 32, 4, 511-515H. curtaHPLCLink
Sex differences in the pharmacological activity of venom from the white-tailed spider (Lampona cylindrata)L. D. Rash, R. G. King, W. C. Hodgsen, Toxicon 2000, 38, 8, 1111-1127L. cylindrataLink

Spider species

Spider speciesFamilyDiscovered
Acanthoscurria paulensisTheraphosidae1963 / J. H. Welsh
Acanthoscurria sternalisTheraphosidae1963 / J. H. Welsh
Cheiracanthium japonicumCheiracanthiidae1991 / K. Hagiwara
Desertosa sp.Lycosidae2020 / Y. M. Forster
Heteropoda davidbowieSparassidae2020 / Y. M. Forster
Hogna carolinensisLycosidae2020 / Y. M. Forster
Hololena curtaAgelenidae1994 / R. Frew
Lampona cylindrataLamponidae2000 / L. D. Rash
Lasiodora klugiTheraphosidae1963 / J. H. Welsh
Latrodectus tredecimguttatusTheridiidae1972 / M. C. Pansa
Lycosa erythrognathaLycosidae1963 / J. H. Welsh
Lycosa praegrandisLycosidae2020 / Y. M. Forster
Lycosa sp.Lycosidae2020 / Y. M. Forster
Phoneutria feraCtenidae1963 / J. H. Welsh
Phoneutria nigriventerCtenidae1973 / S. Schenberg
Pireneitega luctuosaAgelenidae2020 / Y. M. Forster
Vitalius roseusTheraphosidae1963 / J. H. Welsh
Vitalius vellutinusTheraphosidae1963 / J. H. Welsh

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