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IndAc433
General Description
| Name | Value |
|---|
| Level | S-3 / C-1 |
| Discovered | 1991 / H.curta |
| Synonym | HO 359 |
| Molecular formula | C₂₀H₃₃N₅O |
| CAS | 133805-34-2 |
| SMILES | O=C(NCCCCNCCCNCCCN)CC1=CNC2=C1C=CC=C2 |
| InChI | InChI=1S/C20H33N5O/c21-9-5-11-23-13-6-12-22-10-3-4-14-24-20(26)15-17-16-25-19-8-2-1-7-18(17)19/h1-2,7-8,16,22-23,25H,3-6,9-15,21H2,(H,24,26) |
| |
| Precursor 1 [M+H]⁺ | 360.27579 |
| Precursor 2 [M+2H]²⁺ | 180.64153 |
| Precursor 3 | |
| |
| HDX | 6 |
| Precursor HDX 1 [M(D₆)+D]⁺ | 367.31972 |
| Precursor HDX 2 [M(D₆)+2D]²⁺ | 184.66664 |
| Precursor HDX 3 | |
| |
| Rt | 9.02 |
| Rt HDX | 7.52 |
Calculated MS/MS fragments
| # | a | b | c | ta | z | y | tz |
|---|
| 1 | 229.13354 | 211.12297 | 212.10699 | 246.16009 | 58.06513 | 41.03858 | 75.09167 |
| 2 | 286.19139 | 268.18082 | 269.16484 | 303.21794 | 115.12297 | 98.09643 | 132.14952 |
| 3 | 343.24924 | 325.23867 | 326.22269 | 360.27579 | 186.19647 | 169.16993 | 203.22302 |
Additional MS/MS fragments
| m/z | Annotation |
|---|
| 72.08078 | z1’ |
| 112.11208 | y2’ |
| 129.13862 | z2’ |
| 130.06513 | a’ |
| 158.06004 | a0 |
| 342.26522 | bw |
Recorded MS/MS spectra
| pdf | Precursor | Co-eluting | Spider | Source | Author |
|---|
| Data | 360.27634 | | A. aperta | Fauna Laboratories Ltd., KAZ | Y. M. Forster |
| Data | HDX | | A. aperta | Fauna Laboratories Ltd., KAZ | Y. M. Forster |
| Data | 360.27634 | | A. potteri | Fauna Laboratories Ltd., KAZ | Y. M. Forster |
| Data | HDX | | A. potteri | Fauna Laboratories Ltd., KAZ | Y. M. Forster |
| Data | 360.27634 | | H. curta | Fauna Laboratories Ltd., KAZ | Y. M. Forster |
| Data | 180.64208 | | H. curta | Fauna Laboratories Ltd., KAZ | Y. M. Forster |
| Data | HDX | | H. curta | Fauna Laboratories Ltd., KAZ | Y. M. Forster |
| Data | 360.27634 | | Hololena sp. | Spider Pharm, USA | Y. M. Forster |
| Data | 180.64208 | | Hololena sp. | Spider Pharm, USA | Y. M. Forster |
| Data | HDX | | Hololena sp. | Spider Pharm, USA | Y. M. Forster |
References
| Title | Reference | Spider | Name | Content | Link |
|---|
| Paralytic and insecticidal toxins from the funnel web spider, Hololena curta | G. B. Quistad, C. C. Reuter, W. S. Skinner, P. A. Dennis, S. Suwanrumpha, E. W. Fu, Toxicon 1991, 29, 329-336 | H. curta | HO 359 | FAB-MS/MS (ns), Activity-studies | Link |
| Polyamine toxins from spiders and wasps | A. Schäfer, H. Benz, W. Fiedler, A. Guggisberg, S. Bienz, M. Hesse, The Alkaloids 1994, 45, 1-125 | H. curta | HO 359 | Review | Link |
| Acylpolyamines: Mass spectrometric analytical methods for Araneidae spider acylpolyamines | Y. Itagaki, T. Nakajima, Toxin Rev. 2000, 19, 1, 23-52 | H. curta | HO 359 | Review | Link |
| Low molecular mass compounds in spider venom | Y. M. Forster, S. Bienz, L. Bigler, 2020, in preparation | div. | | | Link |
Spider species
| Spider species | Family | Discovered |
|---|
| Agelenopsis aperta | Agelenidae | 2020 / Y. M. Forster |
| Agelenopsis potteri | Agelenidae | 2020 / Y. M. Forster |
| Hololena curta | Agelenidae | 1991 / G. B. Quistad |
| Hololena sp. | Agelenidae | 2020 / Y. M. Forster |