PA34
General Description
| Name | Value |
|---|---|
| Level | S-1 / C-1 |
| Discovered | 1979 / A. robustus |
| Synonym | Spermidine |
| Molecular formula | C₇H₁₉N₃ |
| CAS | 124-20-9 |
| SMILES | NCCCNCCCCN |
| InChI | InChI=1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2 |
| Precursor 1 [M+H]⁺ | 146.16517 |
| Precursor 2 [M+2H]²⁺ | 73.58623 |
| Precursor 3 | |
| HDX | 5 |
| Precursor HDX 1 [M(D₅)+D]⁺ | 152.20283 |
| Precursor HDX 2 [M(D₅)+2D]²⁺ | 77.10819 |
| Precursor HDX 3 | |
| Rt | 1.06 |
| Rt HDX | 1.03 |
Calculated MS/MS fragments
| # | a | b | c | ta | z | y | tz |
|---|---|---|---|---|---|---|---|
| 1 | 58.06513 | 40.05456 | 41.03858 | 75.09167 | 72.08078 | 55.05423 | 89.10732 |
| 2 | 129.13862 | 111.12806 | 112.11208 | 146.16517 | 129.13862 | 112.11208 | 146.16517 |
Additional MS/MS fragments
| m/z | Annotation |
|---|---|
Recorded MS/MS spectra
| Precursor | Co-eluting | Spider | Source | Author | |
|---|---|---|---|---|---|
| Data | 146.16517 | Spermidine 3HCl (CAS 334-50-9) | Fluka | Y. M. Forster | |
| Data | 146.16517 | A. robustus | Alpha Biotoxin, BEL | Y. M. Forster | |
| Data | HDX | A. robustus | Alpha Biotoxin, BEL | Y. M. Forster | |
| Data | 146.16517 | Hololena sp. | Spider Pharm, USA | Y. M. Forster | |
| Data | HDX | Hololena sp. | Spider Pharm, USA | Y. M. Forster | |
| Data | 146.16517 | L. praegrandis | Fauna Laboratories Ltd., KAZ | Y. M. Forster | |
| Data | 146.16517 | Lycosa sp.4 | Fauna Laboratories Ltd., KAZ | Y. M. Forster | |
| Data | 146.16517 | T. clavipes | Spider Pharm, USA | Y. M. Forster | |
| Data | HDX | T. clavipes | Spider Pharm, USA | Y. M. Forster | |
| Data | 146.16517 | P. bistriata | Prof. Dr. Wagner Ferreira dos Santos, BRA | Y. M. Forster | |
| Data | HDX | P. bistriata | Prof. Dr. Wagner Ferreira dos Santos, BRA | Y. M. Forster | |
| Data | 146.16517 | P. mexicanus | Spider Pharm, USA | Y. M. Forster | |
| Data | 146.16517 | P. luctuosa | Fauna Laboratories Ltd., KAZ | Y. M. Forster | |
| Data | HDX | P. luctuosa | Fauna Laboratories Ltd., KAZ | Y. M. Forster | |
| Data | 146.16517 | P. tristis | Spider Pharm, USA | Y. M. Forster | |
| Data | HDX | P. tristis | Spider Pharm, USA | Y. M. Forster |
References
| Title | Reference | Spider | Name | Content | Link |
|---|---|---|---|---|---|
| Analysis of the venom of the Sydney funnel-web spider, Atrax robustus using gas chromatography mass spectrometry | P. H. Duffield, A. M. Duffield, P. R. Carroll, D. Morgans, Biomed. Mass. Spectrom. 1979, 6, 3, 105-108 | A. robustus | GC-MS | link | |
| Polyamines in some tarantula venoms | S. G. Cabbiness, C. W. Gehrke, K. C. Kuo, T. K. Chan, J. E. Hall, S. A. Hudiburg, G. V. Odell, Toxicon 1980, 18, 681-683 | div. | Link | ||
| Determination of biogenic amines in spider venom glands of nine typical Japanese species and chromatographic elution pattern analysis of venomous components | K. Hagiwara, A. Tokita, A. Miwa, N. Kawai, Y. Murata, A. Uchida, T. Nakajima, Jpn. J. Sanit. Zool. 1991, 42, 2, 77-84 | div. | HPLC | link | |
| Novel linear and branched polyamines in the extremely thermophilic eubacteria Thermoleophilum, Bacillus and Hydrogenobacter | K. Hamana, M. Niitsu, S. Matsuzaki, K. Samejima, Y. Igarashi, T. Kodama, Biochem. J. 1992, 284, 741-747 | — | HPLC, GC | Link | |
| The components of the venom of a spider Scodra griseipes. 1. Analysis of low molecular weight products using gas chromatography/ mass spectrometry | C. Lange, C. Paris, M.-L. Celerier, Rapid Commun. Mass Spectrom. 1992, 6, 289-292 | S. calceatum griseipes | GC-MS | link | |
| Polyamine analysis for chemotaxonomy of thermophilic eubacteria: Polyamine distribution profiles within the orders Aquificales, Thermotogales, Thermodesulfobacteriales, Thermales, Thermoanaerobacteriales, Clostridiales and Bacillales | R. Hosoya, K. Hamana, M. Niitsu, T. Itho, J. Gen. Appl. Microbiol. 2004, 50, 271-287 | — | HPLC, GC | Link | |
| Venom composition and strategies in spiders: Is everything possible? | L. Kuhn-Nentwig, R. Stöcklin, W. Nentwig, Adv. Insect Physiol. 2011, 40, 1-86. | putrescine | Review | Link | |
| Elucidation of the structure and synthesis of neuroprotective low molecular mass components of the Parawixia bistriata spider venom | Y. M. Forster, J. L. Green, A. Khatiwada, J. L. Liberato, P. A. Narayana Reddy, J. M. Salvino, S. Bienz, L. Bigler, W. Ferreira dos Santos, A. C. K. Fontana, ACS Chem Neurosci., 2020 | P. bistriata | ESI-MS/MS | Link | |
| Low molecular mass compounds in spider venom | Y. M. Forster, S. Bienz, L. Bigler, 2020, in preparation | div. | Link |
Spider species
| Spider species | Family | Discovered |
|---|---|---|
| Agelena labyrinthica | Agelenidae | 1991 / K. Hagiwara |
| Allagelena opulenta | Agelenidae | 1991 / K. Hagiwara |
| Aphonopelma emilia* | Theraphosidae | 1980 / S. G. Cabbiness |
| Aphonopelma hentzi | Theraphosidae | 1980 / S. G. Cabbiness |
| Aphonopelma sp. | Theraphosidae | 1980 / S. G. Cabbiness |
| Argiope bruennichi | Araneidae | 1991 / K. Hagiwara |
| Atrax robustus | Atracidae | 1979 / P. H. Duffield |
| Dolomedes sulfureus | Pisauridae | 1991 / K. Hagiwara |
| Loxosceles rufescens | Sicariidae | 1991 / K. Hagiwara |
| Lycosa praegrandis | Lycosidae | 2020 / Y. M. Forster |
| Lycosa sp. | Lycosidae | 2020 / Y. M. Forster |
| Neoscona nautica | Araneidae | 1991 / K. Hagiwara |
| Nephila clavata | Araneidae | 1991 / K. Hagiwara |
| Trichonephila clavipes | Araneidae | 2020 / Y. M. Forster |
| Parawixia bistriata | Araneidae | 2020 / Y. M. Forster |
| Physocyclus mexicanus | Pholcidae | 2020 / Y. M. Forster |
| Pireneitega luctuosa | Agelenidae | 2020 / Y. M. Forster |
| Plectreurys tristis | Plectreuridae | 2020 / Y. M. Forster |
| Stromatopelma calceatum griseipes | Theraphosidae | 1992 / C. Lange |